Pathophysiological basis and promise of experimental therapies for Gulf War Illness, a chronic neuropsychiatric syndrome in veterans.
Psychopharmacology (Berl).
2023 Apr;240(4):673-697. doi: 10.1007/s00213-023-06319-5. Epub 2023 Feb 15. Review. PubMed PMID:
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Intranasally administered human MSC-derived extracellular vesicles inhibit NLRP3-p38/MAPK signaling after TBI and prevent chronic brain dysfunction.
Brain Behav Immun.
2023 Feb;108:118-134. doi: 10.1016/j.bbi.2022.11.014. Epub 2022 Nov 24. PubMed PMID:
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Brain-Specific Increase in Leukotriene Signaling Accompanies Chronic Neuroinflammation and Cognitive Impairment in a Model of Gulf War Illness.
Front Immunol.
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Oral Nano-Curcumin in a Model of Chronic Gulf War Illness Alleviates Brain Dysfunction with Modulation of Oxidative Stress, Mitochondrial Function, Neuroinflammation, Neurogenesis, and Gene Expression.
Aging Dis.
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Promise of metformin for preventing age-related cognitive dysfunction.
Neural Regen Res.
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Neuroimmune mechanisms of cognitive impairment in a mouse model of Gulf War illness.
Brain Behav Immun.
2021 Oct;97:204-218. doi: 10.1016/j.bbi.2021.07.015. Epub 2021 Jul 29. PubMed PMID:
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Moderate, intermittent voluntary exercise in a model of Gulf War Illness improves cognitive and mood function with alleviation of activated microglia and astrocytes, and enhanced neurogenesis in the hippocampus.
Brain Behav Immun.
2021 Oct;97:135-149. doi: 10.1016/j.bbi.2021.07.005. Epub 2021 Jul 8. PubMed PMID:
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Melatonin improves brain function in a model of chronic Gulf War Illness with modulation of oxidative stress, NLRP3 inflammasomes, and BDNF-ERK-CREB pathway in the hippocampus.
Redox Biol.
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Metformin treatment in late middle age improves cognitive function with alleviation of microglial activation and enhancement of autophagy in the hippocampus.
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Extracellular Vesicles in the Forebrain Display Reduced miR-346 and miR-331-3p in a Rat Model of Chronic Temporal Lobe Epilepsy.
Mol Neurobiol.
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Monosodium luminol reinstates redox homeostasis, improves cognition, mood and neurogenesis, and alleviates neuro- and systemic inflammation in a model of Gulf War Illness.
Redox Biol.
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Intranasally Administered Human MSC-Derived Extracellular Vesicles Pervasively Incorporate into Neurons and Microglia in both Intact and Status Epilepticus Injured Forebrain.
Int J Mol Sci.
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A Model of Chronic Temporal Lobe Epilepsy Presenting Constantly Rhythmic and Robust Spontaneous Seizures, Co-morbidities and Hippocampal Neuropathology.
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Neuroinflammation in Gulf War Illness is linked with HMGB1 and complement activation, which can be discerned from brain-derived extracellular vesicles in the blood.
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Novel Insights on Systemic and Brain Aging, Stroke, Amyotrophic Lateral Sclerosis, and Alzheimer's Disease.
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Neural Stem Cell or Human Induced Pluripotent Stem Cell-Derived GABA-ergic Progenitor Cell Grafting in an Animal Model of Chronic Temporal Lobe Epilepsy.
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Voluntary Running Exercise-Mediated Enhanced Neurogenesis Does Not Obliterate Retrograde Spatial Memory.
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Moderate Running Exercise Improves Cognitive, Memory And Mood Function With Increased Neurogenesis In A Gulf War Illness Model.
Cell transplantation. 2016; 25(4):764-765.
Resveratrol Treatment after Status Epilepticus Restrains Neurodegeneration and Abnormal Neurogenesis with Suppression of Oxidative Stress and Inflammation.
Sci Rep.
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Resveratrol prevents age-related memory and mood dysfunction with increased hippocampal neurogenesis and microvasculature, and reduced glial activation.
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Running Exercise Does Not Promote Forgetting in Adult Rats.
Cell transplantation. 2015; 24(4):763.
Corrigendum: Blood brain barrier dysfunction and delayed neurological deficits in mild traumatic brain injury induced by blast shock waves.
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Object location and object recognition memory impairments, motivation deficits and depression in a model of Gulf War illness.
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Serum protein profile studies in monitoring of tumor response to radiotherapy in cervical cancers.
Medical Laser Application. 2009; 24(3):165-174.
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Biopolymers.
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Raman spectroscopy of breast tissues.
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An overview on applications of optical spectroscopy in cervical cancers.
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Raman Spectroscopy of tissues collected at different fractions of Radiation Therapy: Response assessment to radiotherapy in cervix cancers.
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