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Abstract

Before the international spread of monkeypox in May 2022, PCR kits for the detection of orthopoxviruses, and specifically monkeypox virus, were rarely available. Here we describe the evaluation of 11 recently developed commercially available PCR kits for the detection of monkeypox virus DNA. All tested kits are currently intended for research use only and clinical performance still needs to be assessed in more detail, but all were suitable for diagnostics of monkeypox virus, with variations in specificity rather than sensitivity.

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/content/10.2807/1560-7917.ES.2022.27.45.2200816
2022-11-10
2024-04-26
http://instance.metastore.ingenta.com/content/10.2807/1560-7917.ES.2022.27.45.2200816
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Evaluation of 11 commercially available PCR kits for the detection of monkeypox virus DNA, Berlin, July to September 2022
<p class="citation"> <span>Citation style for this article:</span> <span class="meta-value authors"> <a href="/search?value1=Janine+Michel&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Michel Janine</a>, <a href="/search?value1=Angelina+Targosz&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Targosz Angelina</a>, <a href="/search?value1=Thomas+Rinner&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Rinner Thomas</a>, <a href="/search?value1=Daniel+Bourquain&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Bourquain Daniel</a>, <a href="/search?value1=Annika+Brinkmann&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Brinkmann Annika</a>, <a href="/search?value1=Jilian+Amber+Sacks&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Sacks Jilian Amber</a>, <a href="/search?value1=Lars+Schaade&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Schaade Lars</a>, <a href="/search?value1=Andreas+Nitsche&option1=author&noRedirect=true" class="nonDisambigAuthorLink">Nitsche Andreas</a></span>. Evaluation of 11 commercially available PCR kits for the detection of monkeypox virus DNA, Berlin, July to September 2022 . <a href="/content/ecdc">Euro Surveill.</a> 2022;27(45):pii=2200816. <a href="https://doi.org/10.2807/1560-7917.ES.2022.27.45.2200816" title="doi link" target="_blank">https://doi.org/10.2807/1560-7917.ES.2022.27.45.2200816</a> <span class="ES_Article_citation"> <span class="generated">Received</span>: 20 Oct 2022;&nbsp;&nbsp; <span class="generated">Accepted</span>: 07 Nov 2022 </span> </p>
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