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Sahithi Attaluri
Sahithi Attaluri
Senior Research Associate
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Year
Extracellular vesicles from human iPSC-derived neural stem cells: miRNA and protein signatures, and anti-inflammatory and neurogenic properties
R Upadhya, LN Madhu, S Attaluri, DLG Gitaí, MR Pinson, M Kodali, ...
Journal of extracellular vesicles 9 (1), 1809064, 2020
1042020
Human induced pluripotent stem cell-derived MGE cell grafting after status epilepticus attenuates chronic epilepsy and comorbidities via synaptic integration
D Upadhya, B Hattiangady, OW Castro, B Shuai, M Kodali, S Attaluri, ...
Proceedings of the National Academy of Sciences 116 (1), 287-296, 2019
992019
Metformin treatment in late middle age improves cognitive function with alleviation of microglial activation and enhancement of autophagy in the hippocampus
M Kodali, S Attaluri, LN Madhu, B Shuai, R Upadhya, JJ Gonzalez, X Rao, ...
Aging Cell 20 (2), e13277, 2021
932021
Intranasally administered human MSC-derived extracellular vesicles pervasively incorporate into neurons and microglia in both intact and status epilepticus injured forebrain
M Kodali, OW Castro, DK Kim, A Thomas, B Shuai, S Attaluri, R Upadhya, ...
International journal of molecular sciences 21 (1), 181, 2019
872019
Chronic oxidative stress, mitochondrial dysfunction, Nrf2 activation and inflammation in the hippocampus accompany heightened systemic inflammation and oxidative stress in an …
GA Shetty, B Hattiangady, D Upadhya, A Bates, S Attaluri, B Shuai, ...
Frontiers in molecular neuroscience 10, 182, 2017
852017
Neuroinflammation in Gulf War Illness is linked with HMGB1 and complement activation, which can be discerned from brain-derived extracellular vesicles in the blood
LN Madhu, S Attaluri, M Kodali, B Shuai, R Upadhya, D Gitai, AK Shetty
Brain, behavior, and immunity 81, 430-443, 2019
702019
Melatonin improves brain function in a model of chronic Gulf War Illness with modulation of oxidative stress, NLRP3 inflammasomes, and BDNF-ERK-CREB pathway in the hippocampus
LN Madhu, M Kodali, S Attaluri, B Shuai, L Melissari, X Rao, AK Shetty
Redox Biology 43, 101973, 2021
652021
Monosodium luminol reinstates redox homeostasis, improves cognition, mood and neurogenesis, and alleviates neuro-and systemic inflammation in a model of Gulf War Illness
AK Shetty, S Attaluri, M Kodali, B Shuai, GA Shetty, D Upadhya, ...
Redox biology 28, 101389, 2020
492020
A model of chronic temporal lobe epilepsy presenting constantly rhythmic and robust spontaneous seizures, co-morbidities and hippocampal neuropathology
D Upadhya, M Kodali, D Gitai, OW Castro, G Zanirati, R Upadhya, ...
Aging and disease 10 (5), 915, 2019
312019
Intranasally administered human MSC-derived extracellular vesicles inhibit NLRP3-p38/MAPK signaling after TBI and prevent chronic brain dysfunction
M Kodali, LN Madhu, RL Reger, B Milutinovic, R Upadhya, JJ Gonzalez, ...
Brain, behavior, and immunity 108, 118-134, 2023
282023
Wwox deletion leads to reduced GABA-ergic inhibitory interneuron numbers and activation of microglia and astrocytes in mouse hippocampus
T Hussain, H Kil, B Hattiangady, J Lee, M Kodali, B Shuai, S Attaluri, ...
Neurobiology of disease 121, 163-176, 2019
282019
Chronobiology of limbic seizures: Potential mechanisms and prospects of chronotherapy for mesial temporal lobe epilepsy
DLG Gitai, TG de Andrade, YDR Dos Santos, S Attaluri, AK Shetty
Neuroscience & Biobehavioral Reviews 98, 122-134, 2019
232019
Oral nano-curcumin in a model of chronic Gulf War illness alleviates brain dysfunction with modulation of oxidative stress, mitochondrial function, neuroinflammation …
S Attaluri, M Arora, LN Madhu, M Kodali, B Shuai, L Melissari, R Upadhya, ...
Aging and Disease 13 (2), 583, 2022
162022
Moderate, intermittent voluntary exercise in a model of Gulf War Illness improves cognitive and mood function with alleviation of activated microglia and astrocytes, and …
M Kodali, V Mishra, B Hattiangady, S Attaluri, JJ Gonzalez, B Shuai, ...
Brain, behavior, and immunity 97, 135-149, 2021
122021
Brain-specific increase in leukotriene signaling accompanies chronic neuroinflammation and cognitive impairment in a model of Gulf war illness
S Attaluri, R Upadhya, M Kodali, LN Madhu, D Upadhya, B Shuai, ...
Frontiers in Immunology 13, 853000, 2022
92022
Intranasally administered extracellular vesicles from human induced pluripotent stem cell-derived neural stem cells quickly incorporate into neurons and microglia in 5xFAD mice
S Attaluri, J Jaimes Gonzalez, M Kirmani, AD Vogel, R Upadhya, M Kodali, ...
Frontiers in Aging Neuroscience 15, 1200445, 2023
72023
Grafted hPSC-derived GABA-ergic interneurons regulate seizures and specific cognitive function in temporal lobe epilepsy
D Upadhya, S Attaluri, Y Liu, B Hattiangady, OW Castro, B Shuai, Y Dong, ...
npj Regenerative Medicine 7 (1), 38, 2022
72022
A single intranasal dose of human mesenchymal stem cell-derived extracellular vesicles after traumatic brain injury eases neurogenesis decline, synapse loss, and BDNF-ERK-CREB …
M Kodali, LN Madhu, RL Reger, B Milutinovic, R Upadhya, S Attaluri, ...
Frontiers in Molecular Neuroscience 16, 1185883, 2023
42023
Extracellular vesicles from hiPSC-NSCs can prevent peripheral inflammation-induced cognitive dysfunction with inflammasome inhibition and improved neurogenesis in the hippocampus
G Ayyubova, M Kodali, R Upadhya, LN Madhu, S Attaluri, Y Somayaji, ...
Journal of Neuroinflammation 20 (1), 297, 2023
12023
Intranasally Administered EVs from hiPSC-derived NSCs Alter the Transcriptomic Profile of Activated Microglia and Conserve Brain Function in an Alzheimer's Model
LN Madhu, M Kodali, R Upadhya, S Rao, B Shuai, Y Somayaji, S Attaluri, ...
bioRxiv, 2024.01. 18.576313, 2024
2024
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