It's time to stop using nitrous oxide for pediatric mask induction

Paediatr Anaesth. 2024 Feb;34(2):104-107. doi: 10.1111/pan.14778. Epub 2023 Oct 4.

Abstract

Background: Mask induction of anesthesia for pediatric patients has included the use of nitrous oxide since the inception of pediatric anesthesia. However, the use of nitrous oxide precludes adequate preoxygenation. Additionally, pediatric physiology (less Functional Residual Capacity, higher oxygen consumption), increased risk of laryngospasm and lack of intravenous access increase the risk of a severe airway complication in the event of airway occlusion. Nitrous oxide does not facilitate tranquil mask placement on an unwilling child and does not meaningfully speed mask induction. Exposure to nitrous oxide has potential occupational health concerns and nitrous oxide has significant environmental detriment.

Conclusion: Utilizing other, evidence-based, techniques to facilitate tranquil mask placement will assure that patients have a pleasant induction experience and avoiding nitrous oxide will reduce the environmental impact, as well as improve the safety of, pediatric mask induction.

Keywords: airway management; child; environment; general anesthesia; greenhouse gas; laryngismus; nitrous oxide; sustainability.

MeSH terms

  • Anesthesia, General
  • Anesthetics, Inhalation* / pharmacology
  • Child
  • Humans
  • Methyl Ethers*
  • Nitrous Oxide
  • Sevoflurane

Substances

  • Nitrous Oxide
  • Anesthetics, Inhalation
  • Sevoflurane
  • Methyl Ethers