Use of Uncrossmatched Cold-Stored Whole Blood in Injured Children With Hemorrhagic Shock

Christine M Leeper; Mark H Yazer; Franklyn P Cladis; Richard Saladino; Darrell J Triulzi; Barbara A Gaines

doi:10.1001/jamapediatrics.2017.5238

Use of Uncrossmatched Cold-Stored Whole Blood in Injured Children With Hemorrhagic Shock

JAMA Pediatr. 2018 May 1;172(5):491-492. doi: 10.1001/jamapediatrics.2017.5238.

Authors

Christine M Leeper^{1

2}, Mark H Yazer³, Franklyn P Cladis⁴, Richard Saladino⁵, Darrell J Triulzi³, Barbara A Gaines^{1

2}

Affiliations

¹ Department of Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
² Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
³ Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
⁴ Department of Anesthesia, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.
⁵ Department of Emergency Medicine, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania.

Abstract

This study compares the time to transfusion in traumatically injured children receiving uncrossmatched whole blood with time to infusion in a historical cohort that received blood components.

MeSH terms

Adolescent
Blood Grouping and Crossmatching
Blood Preservation / methods*
Blood Transfusion / methods*
Child
Child, Preschool
Cold Temperature
Emergency Service, Hospital
Female
Humans
Injury Severity Score
Length of Stay / statistics & numerical data
Male
Resuscitation / methods
Shock, Hemorrhagic / etiology
Shock, Hemorrhagic / therapy*
Time Factors
Wounds and Injuries / complications
Wounds and Injuries / therapy*